Thyroglobulin, Serum or Plasma with Reflex to LC-MS/MS or CIA
Thyroglobulin, Thyroglobulin antibody
Specimens negative for thyroglobulin antibodies (TgAb) are tested for thyroglobulin (Tg) by chemiluminescent immunoassay (CIA) using the Beckman Coulter Access® DxI method. Specimens with TgAb results above the upper reference limit are tested for Tg by high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS). Results obtained with different test methods or kits cannot be used interchangeably. Tg results, regardless of concentration, should not be interpreted as absolute evidence for the presence or absence of papillary or follicular thyroid cancer. Tg testing is not recommended for use as a screening procedure to detect the presence of thyroid cancer in the general population.
Specimen Collection Requirements
Serum, one 6 mL gold (SST) top tube, also acceptable Plasma, green (sodium or lithium heparin) top tube.
Allow serum to clot, centrifuge, aliquot serum or plasma into plastic tube and freeze.
EDTA Plasma, any fluid other than noted above
Ambient: 8 hours; Refrigerated: 1 week; Frozen: 6 months
Testing Information
Quantitative Chemiluminescent Immunoassay/High Performance Chromatography-Tandem Mass Spectrometry
Reference Values
Last Updated:
Wednesday, January 22, 2020 09:22:46 PM
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