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*Valproic Acid

Mnemonic

VALP

Synonym

Depakane® - Depakote - Valproate

Guidelines

For information on when to collect specimen, please refer to Therapeutic Drug Monitoring (TDM) Guidelines for Pediatrics and Adults.

Specimen Collection Requirements

Collect

Serum or Plasma, one 5.0 mL gold (SST), 7.0 mL red or 3.0 mL mint green (lithium heparin, PST) top tube

Handling

Allow serum to clot completely at room temperature (minimum: SST - 30 minutes and red top tubes - 60 minutes). Centrifuge and separate serum or plasma from cells ASAP.

Preferred Volume

1.0 mL Serum/Plasma

Minimum Volume

0.25 mL Serum/Plasma (0.60 mL minimum whole blood draw)

Transport

Refrigerated (2-8°C)

Rejection Criteria

Grossly hemolyzed specimens

Stability

AFTER SEPARATION FROM CELLS: Room Temperature (18-26°C): 2 days; Refrigerated (2-8°C): 7 days; Frozen (≤ -20°C): 1 year

Testing Information

Performed

7 days/week

Reported

24 hours

Method

EMIT

Reference Values

Therapeutic Range

Toxic Levels

CPT Codes

80164

Last Updated: Tuesday, January 26, 2021 12:45:09 AM


Client Services: 503-413-1234