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Zinc Protoporphyrin

Mnemonic

ZPP

Synonym

Zinc Protoporphyrins Whole Blood – ZnPP - ZPPH

Includes

  • Zinc Protoporphyrin, Blood
  • Zinc Protoporphyrin (ZPP), Whole Blood Ratio

Specimen Collection Requirements

Collect

EDTA Whole Blood, one 4.0 mL lavender (EDTA), 6.0 mL royal blue (K2EDTA or Na2EDTA), or 3.0 mL tan (K2EDTA) top tube

Use royal blue top tube when also testing for lead.

Handling

Guard the specimen against environmental contamination. Keep the specimen sealed in the original container.  Do not separate the plasma from the red blood cells.

Preferred Volume

1.0 mL EDTA Whole Blood

Minimum Volume

0.2 mL EDTA Whole Blood

Transport

Refrigerated (2-8 ºC)

Rejection Criteria

  • Specimens other than EDTA whole blood
  • Hemolyzed specimens
  • Clotted specimens
  • Frozen specimens

Stability

Room Temperature (18-26°C): 30 hours; Refrigerated (2-8°C): 5 weeks; Frozen (≤ -20°C): Unacceptable

Testing Information

Performed

Mon-Fri

Reported

2-5 days

Method

Hematofluorometry

Referral Lab

ARUP 0020614

Reference Values

Reference Values

  • ZPP:  0-40 µg/dL
  • ZPP/Heme Ratio:  0-69 µmol ZPP/mol heme

Comments

For occupational exposure to lead, OSHA requires ZPP whole blood concentration to be reported in units of µg/dL. For adults, conversion of ZPP to units of µg/dL assumes a hematocrit of 45%.

CPT Codes

84202

Last Updated: Wednesday, November 27, 2019 07:35:22 PM


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