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Legacy Research Institutional Biosafety Committee

The Legacy Research Institutional Biosafety Committee (IBC) is responsible for the review and approval of all research involving recombinant or synthetic nucleic acid molecules (e.g., rDNA) that utilize Legacy Health facilities, resources or patients. This includes laboratory rDNA research and human gene therapy research. The IBC also reviews all research projects at the Legacy Research Institute that involve non-recombinant risk group 2 and higher infectious agents.

Instructions for starting the IBC review process:

  • Request an IBC Protocol application form from the research laboratory safety specialist at He will forward the required form(s) and instructions.
  • Complete the form and have it signed by the principal investigator (PI).
  • Return the form to the research laboratory safety specialist.

If you require guidance for completing the form, please contact the research laboratory safety specialist.

Note that human gene therapy research is also subject to IRB oversight, and the agent used requires prior FDA approval.

IBC Contact: John Ost, MAT, Research Laboratory Safety Specialist
Telephone: (503) 413-5409


  1. NIH Office of Science Policy (OSP)
  2. NIH Guidelines for Research Involving Recombinant & Synthetic Nucleic Acids
  3. Legacy Institutional Review Board