CCM OPEN HF Registry
| Clinical Trial Title | CCM Technologies OPEN HF Registry: Observational Patient Evaluation of CCM Therapy for Heart Failure |
| Trial Status | Open to Enrollment |
| Start Date | 05/12/2026 |
| Location | Legacy Emanuel Medical Center |
| Trial Type | Heart Disease/Cardiology |
| Specific Condition | Heart failure |
| Description | This is a registry for an FDA-approved heart failure therapy called cardiac contractility modulation, also known as CCM therapy. Heart failure is treated with medications to improve the strength of the heart muscle and reduce the amount of work the heart must do. However, medications are not always successful in making heart failure patients feel better. The CCM Device is indicated for patients that remain symptomatic despite best efforts to treat the condition with medications. The registry has been designed to evaluate the long-term safety and efficacy of CCM therapy in a real-world setting. This is a global, prospective and retrospective, multicenter, single-arm, observational study intended to include patients who will receive/have received CCM therapy with an Impulse Dynamics system, including future CCM technologies (e.g. CCM-D), for a follow-up period of at least 5 years. This registry will uniformly gather real-world data from clinical sites adhering to standard-of-care protocols for subjects receiving CCM therapy. |
| Eligibility Criteria | Inclusion Criteria:
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| IRB Number | 10920 |
| Notes | |
| Principal Investigator | Brendan Daly, MD |
| Contact Name | Jon Cook |
| Contact Phone | 503-413-8330 |
| Contact Fax | 503-413-6861 |
| Contact E-Mail | johcook@lhs.org |
