Legacy Research Institute

JOIN THE P3 STUDY

The Portland Progression Project (P3) is a long-term study that aims to develop methods for predicting the rate of vision loss in patients with glaucoma, earlier and more accurately than is currently possible. A major goal of the study is to build the ability to first identify and then predict which patients will progress rapidly and are therefore most in need of early testing and treatment decisions.

To refer a patient, or for more information, contact:
Cindy Albert: Tel: 503-413-6457, Email: calbert@deverseye.org

We are especially eager to recruit patients from minority groups (African American, Asian, Latino, American Natives) into this study.

Participation Requirements:

• Two visits each year, six months apart.
• Dilation of pupils on each visit.
• Testing includes, but not limited to: Visual Field, Ocular photos, three different scanning lasers

Inclusion Criteria:

Either:

• A clinical diagnosis of primary open angle glaucoma (POAG)
• Visual field deficits by GHT or PSD
• Mean deviation no worse than -10dB
  Or:
• Ocular Hypertension (IOP ≥ 22)
  plus at least 1 of the following:
• Large cup/disk ratio for ONH size
• Suspicious ONH appearance
• Cup asymmetry (≥ 0.2)
• Disk hemorrhage
• Notching of ONH rim
• Nerve fiber layer thinning/defect
• Immediate family history of POAG
• Age ≥ 70 (please be selective)
• Vascular, need 2 or more of the following: Migraine, hypertension or heart disease, Reynaud’s Syndrome

Exclusion Criteria:

• Visual acuity worse than 20/40 in either eye
• Diabetes (diet, oral or ID) or other major systemic disease
• Co-existing eye disease
• Ocular surgery (uncomplicated glaucoma or cataract surgery OK)
• Secondary glaucomas
• Long term plaquenil use
• Other pathologies or medications that are known to affect the visual field or optic nerve head