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Scientists

Emmanuel Akporiaye, Ph.D.

Emmanuel T. Akporiaye, Ph.D.

Adjunct Scientist, Legacy Research Institute
Founder and CEO, Veana Therapeutics Inc.

Research Interests and Expertise

  • Dr. Akporiaye's research is focused on understanding the interactions between cancer cells and immune cells that favour tumor growth and progression and developing novel therapies that are safe, effective, and less toxic while at the same time ensuring that the patient's quality of life is not compromised.
Michael Bottlang, PhD

Michael Bottlang, Ph.D.

Director
Legacy Biomechanics Laboratory
Research Interests and Expertise
  • Bone fracture treatment
  • Prevention of traumatic brain injury
  • Mechano-active tissue engineering
Claude Burgoyne, MD

Claude F. Burgoyne, M.D.

Senior Scientist
Van Buskirk Chair for Ophthalmic Research
Director, Optic Nerve Head Research Laboratory
Devers Eye Institute
Discoveries in Sight Research Laboratories

Research Interests and Expertise
  • Pathophysiology of glaucomatous optic nerve head damage
  • Optic nerve head biomechanics and blood flow
  • Optic nerve head aging
  • Optic nerve head imaging
  • Clinical examination of the optic nerve head tissues
Megan Cahn, PhD

Megan Cahn, Ph.D.

Clinical Outcomes Research Scientist
Legacy Research Institute
Research Interests and Expertise
  • Health services & policy research
  • Health & health care equity
  • Program evaluation
  • Sexual & reproductive health
  • Behavioral health
Priya Chaudhary, PhD

Priya Chaudhary, PhD

Research Scientist
Optic Nerve Head Research Laboratory
Devers Eye Institute
Discoveries in Sight Research Laboratories
Research Interests and Expertise
  • Neuroinflammation
  • Glaucoma
  • Glial cell biology
  • Drug discovery
  • Multiple sclerosis
Shaban Demirel, OD, PhD

Shaban Demirel, O.D. Ph.D.

Director of Clinical Research
Legacy Research Institute

Research Interests and Expertise
  • Clinical outcomes research
  • Data analysis and statistics
  • Machine learning and Artificial Intelligence applications in health care data
  • Clinical and basic psychophysics
  • Diagnostic device development
  • Glaucoma detection, progression and pathophysiology
Brad Fortune, OD, PhD

Brad Fortune, O.D., Ph.D.

Senior Scientist and Director
Electrodiagnostic Services
Discoveries in Sight Research Laboratories

Research Interests and Expertise
  • Measurement of vision function in human glaucoma and experimental models of glaucoma
  • Electrophysiological assessment of vision function in human and experimental retinal disease models
  • Imaging retinal nerve fiber layer and optic disc structure, correlations with vision function
  • Glaucoma pathogenesis
Stuart Gardiner, PhD

Stuart K. Gardiner, Ph.D.

Assistant Scientist
Co-Director of Clinical Epidemiology & Biostatistics
Devers Eye Institute
Discoveries in Sight Research Laboratories
Research Interests and Expertise
  • Glaucoma Diagnostics
  • Functional testing in glaucoma
  • Structural testing in glaucoma
  • Glaucomatous pathophysiology
  • Measuring progression in glaucoma
  • Structure-function relationships in glaucoma
  • Data analysis and statistics
Soren Impey, PhD

Soren Impey, PhD

Associate Scientist
R.S. Dow Neuroscience Laboratories
Legacy Research Institute

Research Interests and Expertise
  • Functional genomic studies of non-coding RNAs associated with plasticity and epilepsy
  • Dynamic histone and DNA methylation in plasticity and neurodegenerative disorders
  • CREB-regulated microRNAs and their target gene networks
  • Role of OTX2-regulated transcription in Parvalbumin neuron plasticity
Charles Keller, MD

Charles Keller, MD

Adjunct Scientist, Legacy Research Institute
Scientific Director, Children’s Cancer Therapy Development Institute

Research Interests and Expertise
  • Childhood cancer
  • Sarcoma
  • Malignant brain tumors
  • Functional genomics
Robert Kinast, MD

Robert M. Kinast, M.D.

Clinical Scientist, Legacy Research Institute
Associate Director, Glaucoma Fellowship, Legacy Devers Eye Institute
Clinical Associate Professor, OHSU Casey Eye Institute

Research Interests and Expertise
  • Medical Devices
  • Medication adherence
  • Patient Satisfaction
  • Medication Compounding
  • Angle Closure Glaucoma
Steve Mansberger, MD

Steven L. Mansberger, M.D., M.P.H.

Chenoweth Chair of Ophthalmology, Director of Glaucoma Services, Director of Glaucoma Fellowship, Legacy Devers Eye Institute 
Senior Scientist, Discoveries in Sight, Legacy Research Institute
Clinical Vice-President, Legacy Health

Research Interests and Expertise
  • Functional testing of glaucoma
  • Prevalence of eye disease in populations
  • Health behavior as it relates to glaucoma medication adherence
  • Eye drop administration
  • Biostatistics and epidemiology
Danielle M. Osborne, PhD

Danielle M. Osborne, PhD

Staff Scientist
R.S. Dow Neuroscience Laboratories
Legacy Research Institute
Research Interests and Expertise
  • Obesity-mediated susceptibility to Alzheimer's Disease
  • Hippocampal metabolism
  • Sex differences
  • Stress effects in the hippocampus
Adie Rae (Wilson-Poe), PhD

Adie Rae (Wilson-Poe), Ph.D.

Assistant Scientist
R.S. Dow Neuroscience Laboratories
Legacy Research Institute

Research Interests and Expertise
  • Cannabis as a first-line analgesic
  • Harm reduction
  • Cannabis as a Medication-Assisted Therapy
  • Clinically-relevant cannabis research
Carmen Rusinaru, MD, PhD

Carmen Rusinaru, MD, PhD

Senior Scientist
Legacy Research Institute
Research Interests and Expertise
  • Neurorehabilitation and neuroplasticity
  • Risk prediction and preventive medicine
  • Cardiovascular disease and arrhythmias
  • Community-based research
  • Nutrition and healthy lifespan research
Haiying Shen, MD, PhD

Haiying Shen, MD, PhD

Senior Research Scientist
R.S. Dow Neuroscience Laboratories
Legacy Research Institute
Research Interests and Expertise
  • Adenosine-based mechanisms in neurobehavioral disorders
  • Treatment and prevention against epilepsy and its comorbidities
  • Translational Neuropharmacology
  • Adenosine manipulation in malignant tumors
Laura Villasana, PhD

Laura Villasana, PhD

Assistant Scientist
R.S. Dow Neuroscience Laboratories
Legacy Research Institute

Research Interests and Expertise
  • Post-traumatic neurogenesis in hippocampal function after traumatic brain injury
  • Modulation of neurogenesis after traumatic brain injury
  • Long-term effects of traumatic brain injury on neural stem cells & neurogenesis
Lin Wang, MD

Lin Wang, M.D., Ph.D.

Associate Scientist
Ocular Microcirculation Unit 
Devers Eye Institute
Discoveries in Sight Research Laboratories

Research Interests and Expertise
  • Ocular blood flow autoregulation in retina and optic nerve
  • Ocular vascular pathology in glaucoma
  • Astrocytic regulation in ocular blood flow
Hongli Yang, PhD

Hongli Yang, PhD

Research Scientist
Optic Nerve Head Research Laboratory
Devers Eye Institute
Discoveries in Sight Research Laboratories
Research Interests and Expertise
  • Optic nerve head biomechanics, blood flow, and aging
  • Optic nerve head and macular imaging
  • Optic nerve head structural phenotype in healthy, glaucomatous and myopia eyes
  • Machine Learning in glaucoma