Claude Burgoyne, MD is a Glaucoma clinician scientist, Van Buskirk Chair for Ophthalmic Research and Director of the Optic Nerve Head Research Laboratory at the Legacy Devers Eye Institute in Portland, Oregon. After an undergraduate Bachelor of Arts degree in Architecture and Medical School at the University of Minnesota, he pursued Ophthalmology residency training at the University of Pittsburgh and Glaucoma Fellowship training at the Wilmer Eye Institute at the Johns Hopkins Hospitals in Baltimore, MD. For twelve years he was Director of Glaucoma Services at the LSU Eye Center in New Orleans before moving to Devers in 2005.
For the past 20 years his laboratory has been NIH funded to study the effects of aging and experimental glaucoma on the neural and connective tissues of the monkey optic nerve head within 3D histomorphometric reconstructions. This work now extends to studying the cell biology of connective tissue remodeling and axonal insult early in the disease. Building upon its 3D capabilities, his laboratory is also funded to use Optical Coherence Tomography (OCT) to phenotype the deep tissues of the monkey and human optic nerve head and peripapillary sclera.
Dr. Burgoyne's honors include the International Glaucoma Review AIGS Award (2004), the Lewis Rudin Glaucoma Prize (2008), the Alcon Research Institute Award (2010); the American Glaucoma Society 2015 Clinician Scientist Lectureship, and the American Academy of Ophthalmology Achievement Award.
He is an invited member of the Glaucoma Research Society and a Gold Fellow of the Association for Research in Vision and Ophthalmology, (ARVO), for which, he has previously served as Glaucoma Section Trustee and President.
The optic nerve head as a biomechanical structure: a new paradigm for understanding the role of IOP-related stress and strain in the pathophysiology of glaucomatous optic nerve head damage.
Burgoyne CF, Downs JC, Bellezza AJ, Suh JK, Hart RT.
Prog Retin Eye Res. 2005 Jan;24(1):39-73.
The connective tissue phenotype of glaucomatous cupping in the monkey eye - Clinical and research implications.
Yang H, Reynaud J, Lockwood H, Williams G, Hardin C, Reyes L, Stowell C, Gardiner SK, Burgoyne CF.
Prog Retin Eye Res. 2017 Jul;59:1-52.
From clinical examination of the optic disc to clinical assessment of the optic nerve head: a paradigm change.
Chauhan BC, Burgoyne CF.
Am J Ophthalmol 2013;156:218-227 e212.
A biomechanical paradigm for axonal insult within the optic nerve head in aging and glaucoma.
Exp Eye Res. 2011 Aug;93(2):120-32
The morphological difference between glaucoma and other optic neuropathies.
J Neuroophthalmol. 2015 Sep;35 Suppl 1:S8-S21.